Clinical Trial

Pain-Related Fear and Motor Control in Healthy Volunteers

Study acronym: Domokiss
Completed
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Summary
The goal of this clinical trial is to learn how experimentally induced movement-related threat affects emotional, autonomic, and motor responses in healthy adults. The main questions it aims to answer are: * Does movement-related threat change walking performance or upper-limb pointing movements? * Are these effects moderated by participants' level of kinesiophobia? * Does movement-related threat increase apprehension or alter heart rate variability responses? Participants will complete two experimental conditions during one session: a control condition and an experimental condition. In both conditions, inactive transcutaneous electrical nerve stimulation (TENS) electrodes will be placed in the lumbar region. In the experimental condition, participants will receive verbal suggestions about discomfort, movement-evoked pain, and potential unpredictable electrical stimulation to create the threat of pain associated with movement. Participants will complete a baseline assessment of kinesiophobia, followed by walking and pointing tasks, while perceived apprehension and autonomic responses are assessed.
Protocol Amendment History 1 change
critical Trial completed 2026-07-09
Trial Details
NCT Number NCT07636603
Lead Sponsor Universite de Picardie Jules Verne
Conditions Pain-related Fear, Kinesiophobia (Fear of Movement), Movement-Related Threat
Enrollment 26 participants
Start Date 2025-11-03
Primary Completion 2026-07-06 (estimated)
Study Completion 2026-07-06 (estimated)
Updated on ClinicalTrials.gov 2026-07-08