THCV Treatment for Smokers

This study will randomize 32 non-treatment-seeking individuals who smoke cigarettes daily into a randomized, crossover, double-blind, placebo-controlled study testing the safety, tolerability, and initial efficacy of Δ9-tetrahydrocannabivarin (Δ9-THCV).

NCT Number	NCT07636356
Lead Sponsor	University of California, Los Angeles Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Tobacco Use Disorder, Smoking Cessation
Enrollment	32 participants
Start Date	2026-07
Primary Completion	2028-05-31 (estimated)
Study Completion	2028-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-09