Clinical Trial

BIOmarker Based Diagnostic TOOLkit to Personalise Pharmacological Approaches in Congestive Heart Failure: the BIOTOOL-CHF Validation Trial

Not Yet Recruiting
View on ClinicalTrials.gov →
Summary
By the re-analysis, in the BIOTOOL-CHF DISCO study, of a previously enrolled cohort of patients, a Biological Congestion Score (BCS) was newly developed. The BCS integrates four congestion-related biomarkers with key clinical variables. The BIOTOOL-CHF VALID trial is designed to prospectively evaluate whether a BCS-assisted strategy for diuretic management improves clinical outcomes and quality of life in patients with chronic Heart Failure (HF) compared with standard care.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-06-03.
Trial Details
NCT Number NCT07635810
Lead Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions Congestive Heart Failure(CHF)
Enrollment 600 participants
Start Date 2026-07-15
Primary Completion 2027-09-06 (estimated)
Study Completion 2028-12-04 (estimated)
Updated on ClinicalTrials.gov 2026-06-12