Health Effects of Ultra-processed Food Intake

Ultra-processed food (UPF) intake has been related to negative health effects and incresed energy intake in previous intervention studies. Thus, previous studies have seen weight gain from higher UPF intake which obscures the potentital to see effects on cardiometabolic biomarkers, independent of weight changes. The overall aim of this project is to study the causal effects of a high UPF diet, compared to a nutrient-matched low UPF diet, on appetite and cardiometabolic health in a weight-stable context.

NCT Number	NCT07634159
Lead Sponsor	Göteborg University Collaborators: Chalmers University of Technology, Karolinska Institutet
Conditions	Cardiometabolic Risk Factors, Microbiota, Diet Interventions
Enrollment	40 participants
Start Date	2026-08
Primary Completion	2027-12 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-08