Clinical Trial

Photodynamic Therapy as an Adjunct in Periodontal Treatment

Study acronym: PDT-PERIO
Not Yet Recruiting
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Summary
This study aims to evaluate the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis. A split-mouth design will be used, in which one hemiarch receives conventional SRP and the contralateral hemiarch receives SRP combined with aPDT. Clinical periodontal parameters, including probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), plaque index (PI), and gingival index (GI), will be assessed at baseline and 30 days after treatment. The study seeks to determine whether adjunctive aPDT improves periodontal outcomes compared with conventional non-surgical periodontal therapy alone.
Trial Details
NCT Number NCT07633405
Lead Sponsor Universidad Catolica Santiago de Guayaquil
Conditions Periodontitis, Periodontal Disease
Enrollment 30 participants
Start Date 2026-07-28
Primary Completion 2026-08-30 (estimated)
Study Completion 2026-09-27 (estimated)
Updated on ClinicalTrials.gov 2026-06-08