REFRAME: an Emotion Regulation Intervention to Improve Psychological Outcomes in Surrogate Decision-Makers of the Critically Ill

Every year in the United States, millions of adults make crucial medical decisions for loved ones in the intensive care unit while facing extreme emotional stress. This project will assess REFRAME, a brief tablet-based program designed to help decision-makers manage their emotions in these situations. Results from this study may lead to the creation of a widely accessible tool that alleviates emotional suffering and enhances the quality of medical decision-making for families in crisis.

NCT Number	NCT07630844
Lead Sponsor	Case Western Reserve University
Conditions	Critical Illness
Enrollment	387 participants
Start Date	2027-01-04
Primary Completion	2031-04-04 (estimated)
Study Completion	2031-04-04 (estimated)
Updated on ClinicalTrials.gov	2026-06-05