Clinical Trial

A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.

Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
The goal of this trial is to learn if MTX325 can be developed as a potential disease-modifying treatment for Parkinson's Disease. Parts 1-4 complete, Part 5 (multiple doses in patients with Parkinson's Disease) in progress.
Protocol Amendment History 1 change
notable Trial sites expanded: 7 -> 18 locations 2026-07-24
Trial Details
NCT Number NCT07630545
Lead Sponsor Mission Therapeutics
Collaborators: Michael J. Fox Foundation for Parkinson's Research, Parkinson's UK
Conditions Parkinson's Disease (PD), Mild to Moderate Parkinson's Disease, Early Stage Parkinson's Disease
Enrollment 106 participants
Start Date 2023-11-30
Primary Completion 2027-06-30 (estimated)
Study Completion 2027-12-27 (estimated)
Updated on ClinicalTrials.gov 2026-07-29