Isometric Exercise for Delayed Onset Muscle Soreness

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults. The main questions it aims to answer are: * Does isometric exercise reduce pain associated with delayed onset muscle soreness? * Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness? Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS. Participants will: * Undergo a standardized exercise protocol to induce delayed onset muscle soreness. * Be randomly assigned to either an isometric exercise group or a control group. * Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference. * Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

NCT Number	NCT07627152
Lead Sponsor	Istanbul Nisantasi University
Conditions	Delayed Onset Muscle Soreness (DOMS)
Enrollment	40 participants
Start Date	2025-04-01
Primary Completion	2025-07-18 (estimated)
Study Completion	2025-07-18 (estimated)
Updated on ClinicalTrials.gov	2026-06-16