Clinical Trial

Laparoscopic Versus Open Radical Hysterectomy in Early-Stage Cervical Cancer

Study acronym: LAP-OPEN
Completed
View on ClinicalTrials.gov →
Summary
The study aims to compare laparoscopic-assisted radical hysterectomy with open radical hysterectomy in women with early-stage cervical cancer. A total of 60 patients diagnosed with FIGO stage IA1, IA2, and IB1 cervical cancer were enrolled and randomly assigned into two equal groups: laparoscopic surgery and open surgery. All patients underwent total hysterectomy, bilateral adnexectomy, and pelvic lymph node dissection. Perioperative outcomes were evaluated, including operative time, blood loss, complications, and hospital stay, as well as long-term oncological outcomes such as recurrence, recurrence-free survival, and overall survival. Patients were followed for up to three years postoperatively. The findings of this study aim to assess the safety, feasibility, and clinical effectiveness of laparoscopic-assisted surgery compared with the conventional open approach in the management of early-stage cervical cancer.
Trial Details
NCT Number NCT07626996
Lead Sponsor Zagazig University
Conditions Cervical Cancer
Enrollment 60 participants
Start Date 2021-03-01
Primary Completion 2024-01-31 (estimated)
Study Completion 2024-01-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-04