Clinical Trial

The Association Between Amputation Level and Chronic Low Back Pain After Combat-Related Amputation

Study acronym: LEVEL-BACK
Not Yet Recruiting
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Summary
Patients with combat-related lower limb amputations frequently experience chronic low back pain during long-term rehabilitation and prosthetic use. Altered biomechanics, asymmetric loading, gait disturbances, and changes in spinal alignment after limb loss may contribute to the development of persistent back pain. The severity and characteristics of low back pain may vary according to the level of amputation. The LEVEL-BACK Study is a prospective observational study designed to evaluate the relationship between amputation level and chronic low back pain after combat-related amputation. Participants with different levels of lower limb amputation will undergo clinical assessment of low back pain intensity, functional limitations, prosthesis use, and rehabilitation outcomes during follow-up. The goal of the study is to improve understanding of how amputation level influences chronic low back pain after combat-related limb loss and to identify patients at increased risk for persistent spinal pain during rehabilitation.
Trial Details
NCT Number NCT07626294
Lead Sponsor Ukrainian Society of Regional Anesthesia and Pain Therapy
Conditions Low Back Pain, Amputation
Enrollment 300 participants
Start Date 2026-09-15
Primary Completion 2026-09-15 (estimated)
Study Completion 2026-09-15 (estimated)
Updated on ClinicalTrials.gov 2026-06-04