Clinical Trial

Domain-Specific Large Language Model Assistance for Emergency Neurological Diagnosis and Treatment（DEMAND）

Completed
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Summary
This study will evaluate whether Xuanwu-NeuroAid 2.0, a large language model for emergency neurology, can improve 30-day diagnostic quality in adults with acute neurological symptoms. Physicians will be randomly assigned to AI-assisted care or usual care. In the AI-assisted group, the model will provide diagnostic and management suggestions, while physicians will make all final clinical decisions. The usual-care group will receive standard emergency neurology care without large language model assistance.
Protocol Amendment History 4 changes
critical Trial completed 2026-08-08
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-07-09
minor Completion moved earlier: 2026-09-30 -> 2026-08-30 2026-06-12
critical Recruitment opened 2026-06-09
Trial Details
NCT Number NCT07626229
Lead Sponsor Capital Medical University
Conditions Nervous System Diseases
Enrollment 1,381 participants
Start Date 2026-06-09
Primary Completion 2026-08-06 (estimated)
Study Completion 2026-08-06 (estimated)
Updated on ClinicalTrials.gov 2026-08-07