Patient-Ventilator Asynchrony: Occurence and Clinical Impact in Usual Care

The goal of this observational study is to unravel the occurence, impact and relations of Patient-Ventilator Aynchrony (PVA) in mechanically ventilated patients. The main questions it aims to answer are: * How often does PVA occur? * What are relations between clinical characteristics and PVA occurence? * What are relations between PVA occurence and patient outcomes? All questions will be assessed using data collected during the whole course of mechanical ventilation. Mechanically ventilated patients' medical data will be re-used. PVAs will be automatically classified on ventilator waveform data, using validated Deep Breath software.

NCT Number	NCT07624786
Lead Sponsor	Erasmus Medical Center Collaborators: Deep Breath, Catharina Ziekenhuis Eindhoven, Leiden University Medical Center
Conditions	Mechanical Ventilation, Patient-Ventilator Asynchrony
Enrollment	110 participants
Start Date	2026-07-21
Primary Completion	2026-11 (estimated)
Study Completion	2027-02 (estimated)
Updated on ClinicalTrials.gov	2026-08-13