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New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial)

Study acronym: RELIEF
StatusRecruiting
PhaseNot applicable
SponsorCellmedis
Started
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Record status
This record was last updated July 10, 2026 (before its estimated September 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Notable Recruitment opened
    • Secondary endpoints: details revised at 7 of 7 entries
    • Site details revised
    • Study title shortened, about 9 words
    v2
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
2 trials monitored
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The goal of this randomized, double-blind, single-center clinical trial RELEIF is to learn if medical devices work to decrease symptoms of gastroesophageal reflux disease (GERD) in adults' patients. It will also teach us about safety, tolerability and improvement of patient's quality of life during and after taking medical device. The main questions it aims to answer are: * Does medical device relieve reflux symptoms? * Does medical device improve the quality of life of patients with GERD symptoms? Researchers will compare medical device to a placebo (a look-alike substance that contains no drug) to see if medical device works in GERD gastroesophageal reflux disease . Participants will: * Take medical device or a placebo every day (4 times a day) for 14 days * Stop taking medical device or placebo for 7 days (wash out period) * Switch the therapy for medical device or placebo for next 14 days * Visit the clinic 4 times during 35 days of this study for checkups and tests * Keep a diary of their symptoms and the number of times they use a medical device * Fill out the form to collect all necessary data.
Trial Details
NCT Number NCT07624383
Lead Sponsor Cellmedis
Collaborators: Medical Network Sp. z o.o.
Conditions
(from sponsor)
GERD (Gastroesophageal Reflux Disease), NERD, Heartburn, Regurgitation, Gastric
Related terms Gastroesophageal Reflux, Heartburn, Laryngopharyngeal Reflux, Non-Erosive Reflux Disease
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov