Clinical Trial

Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO

Study acronym: UPJO-SWE
Recruiting
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Summary
Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children. Although open pyeloplasty is an effective standard treatment, the degree of postoperative renal functional recovery varies between patients. This prospective observational cohort study will evaluate whether renal cortical shear wave elastography can predict renal functional recovery after open pyeloplasty in children with unilateral primary ureteropelvic junction obstruction. Renal cortical shear wave elastography will be assessed before surgery and during follow-up, and the change in elastography values will be compared with renal isotope findings after surgery. The primary objective is to evaluate the predictive value of the change in renal cortical shear wave elastography from baseline to 3 months after surgery for isotope-defined renal functional recovery at 6 months after open pyeloplasty.
Trial Details
NCT Number NCT07624019
Lead Sponsor Beni-Suef University
Conditions Ureteropelvic Junction Obstruction, Renal Functional Recovery
Enrollment 84 participants
Start Date 2026-05-06
Primary Completion 2027-04 (estimated)
Study Completion 2027-05 (estimated)
Updated on ClinicalTrials.gov 2026-06-03