CAR-T Treatment in Pediatric and Adult Acute Lymphoblastic Leukemia

The goal of this observational study is to evaluate the efficacy of the treatment with approved CAR-T cells in Italy in pediatric and adult patients with acute B-cell lymphoblastic leukemia. The main question it aims to answer is: which is the overall response rate in pediatric and adult patients with acute B-cell lymphoblastic leukemia treated with approved CAR-T cells? Data will be extracted from patients medical records.

NCT Number	NCT07623655
Lead Sponsor	Gruppo Italiano Malattie EMatologiche dell'Adulto
Conditions	Acute Lymphoblastic Leukemia, B-Cell Acute Lymphoblastic Leukaemia
Enrollment	107 participants
Start Date	2026-09-01
Primary Completion	2029-09-01 (estimated)
Study Completion	2029-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-03