Clinical Trial

The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.

Active, Not Recruiting
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Summary
The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults. The study focuses on participants aged 20 to 40 with an infection in a lower back tooth (mandibular first molar) and a small area of bone loss at the root tip. The main questions it aims to answer are: Does the type of tool used to rinse the tooth root canal change how much pain a participant feels after treatment? Does the cleaning method lower the number of painkillers a participant needs to take? Researchers will compare four different rinsing tools-ranging from a standard needle to advanced vacuum and vibration devices-to see if using suction and sound waves can lower pain levels. Participants will: Receive a complete root canal treatment in a single visit Be randomly assigned to one of four cleaning groups (standard rinse, vibration, vacuum, or a combination of both) Rate their pain on a scale of 0 to 10 at five specific times: before the visit, and at 6, 12, 24, and 48 hours after treatment Record how many painkiller tablets (Ibuprofen) they take during the two days following the procedure
Trial Details
NCT Number NCT07623629
Lead Sponsor Future University in Egypt
Conditions Necrotic Pulp With Symptomatic Apical Periodontitis
Enrollment 52 participants
Start Date 2026-01-03
Primary Completion 2026-05-05 (estimated)
Study Completion 2026-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-03