Clinical Trial

Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography

Study acronym: TICTAC
Recruiting
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Summary
Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing. The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration. Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography. Participants will : * have a pep titration with both techniques * be included in the study for 28 days
Trial Details
NCT Number NCT07623590
Lead Sponsor Centre Hospitalier Saint Joseph Saint Luc de Lyon
Conditions ARDS (Acute Respiratory Distress Syndrome)
Enrollment 30 participants
Start Date 2025-04-07
Primary Completion 2027-05-05 (estimated)
Study Completion 2027-05-05 (estimated)
Updated on ClinicalTrials.gov 2026-06-03