GLP-1 RA Cessation and Gastric Ultrasound Findings

This prospective observational study will evaluate the association between the time interval since the last dose of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and residual gastric contents before elective surgery. Adult patients receiving GLP-1 RAs and scheduled for elective non-cardiac surgery under general anesthesia will undergo preoperative point-of-care gastric ultrasound. The study will assess whether longer GLP-1 RA cessation intervals are associated with lower ultrasound-estimated gastric volume and a lower frequency of high-risk gastric contents. Body mass index will also be evaluated as a potential modifier of this association.

NCT Number	NCT07623148
Lead Sponsor	Wonkwang University Hospital
Conditions	Residual Gastric Contents, Delayed Gastric Emptying
Enrollment	186 participants
Start Date	2026-07-01
Primary Completion	2026-07-20 (estimated)
Study Completion	2026-08-04 (estimated)
Updated on ClinicalTrials.gov	2026-08-05