Clinical Trial

Circadian Feeding and Reciprocal Scent Intervention in NICU

Completed
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Summary
Objective: This study evaluated the effects of circadian-aligned feeding and reciprocal scent intervention on premature infants receiving mechanical ventilation and on postpartum depression levels in their mothers. Methods: In this randomized controlled trial, 75 premature infants and their mothers were assigned to reciprocal scent, circadian feeding, or control groups (n=25 each). Interventions were applied for 21 days. Outcomes included time to weaning from mechanical ventilation, weight gain, hydration status, breast milk production, and maternal Edinburgh Postnatal Depression Scale (EPDS) scores.
Trial Details
NCT Number NCT07622459
Lead Sponsor Inonu University
Conditions Prematurity, Mechanical Ventilation
Enrollment 150 participants
Start Date 2025-10-01
Primary Completion 2025-11-01 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-03