Clinical Trial

Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes

Study acronym: CLOCK-PRIME
Completed
View on ClinicalTrials.gov →
Summary
This study will test whether glucose sensor data can be used to identify the time of day when adults with prediabetes are most likely to have high blood sugar after meals. Participants will first wear a continuous glucose monitor and wrist activity monitor and record meal times for 10 days. These data will be used to classify each participant's personal "glycemic vulnerability window," such as morning, evening, or generally variable patterns. Participants will then be randomly assigned to either personalized meal timing plus a short walk after their most vulnerable meal, or to an attention-matched control group receiving sleep hygiene and general step-count advice. The main outcome will be the change in post-meal glucose exposure during each participant's vulnerable window after 4 weeks.
Protocol Amendment History 1 change
critical Trial completed 2026-07-29
Trial Details
NCT Number NCT07618663
Lead Sponsor Shifa International Hospital
Conditions Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes or Diabetes
Enrollment 105 participants
Start Date 2026-06-01
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-07-26 (estimated)
Updated on ClinicalTrials.gov 2026-07-28