Efficacy and Safety of Bailout Intracranial Angioplasty or Stenting After Thrombectomy for Acute Intracranial Atherosclerotic Large Vessel Occlusion (ANGEL-REBOOT 2)

A multicenter, randomized, open-label, blinded-endpoint trial with a concurrent prospective observational cohort to compare bailout intracranial angioplasty or stenting versus standard therapy on functional outcome, stroke recurrence, and mortality in patients with acute intracranial atherosclerotic stenosis-related large vessel occlusion after thrombectomy.

NCT Number	NCT07618052
Lead Sponsor	Feng Gao
Conditions	Intracranial Atherosclerotic Stenosis-Related Large Vessel Occlusion, Acute Ischemic Stroke, Bailout Angioplasty or Stenting
Enrollment	420 participants
Start Date	2026-06-01
Primary Completion	2027-06-01 (estimated)
Study Completion	2028-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-01