Whole-Body Cryotherapy and Isokinetic Performance After Exercise-Induced Fatigue

This randomized crossover study investigated the effects of whole-body cryotherapy (WBC) on isokinetic knee performance following running-induced fatigue in physically active healthy male university students. Participants completed two recovery conditions, WBC and passive rest, on separate days following a standardized treadmill fatigue protocol. Knee extension and flexion strength were assessed using an isokinetic dynamometer at angular velocities of 60°/s and 240°/s. In addition, blood pressure, heart rate, oxygen saturation, and perceived fatigue responses were monitored throughout the recovery period. The study aimed to determine whether WBC improves post-exercise recovery and lower-extremity muscle performance compared with passive rest.

NCT Number	NCT07617857
Lead Sponsor	Biruni University
Conditions	Exercise-Induced Fatigue, Recovery
Enrollment	30 participants
Start Date	2024-09-02
Primary Completion	2025-05-01 (estimated)
Study Completion	2025-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-02