Laboratory Heat Biomarker and Cooling Interventions

Our study has two goals. The first goal is to find a blood test that can detect signs of strain from heat in the body ("a biomarker"). Second, the study team wants to identify types of devices that can help people cool down quickly. By identifying biomarkers for heat strain, scientists can better track and treat the health effects of heat. The study team will identify such biomarkers by simulating, in a laboratory-based environment, the heat and physical work that real-world workers experience. In addition, the study team plans to test two cooling technologies that might keep people cool during physical activity.

NCT Number	NCT07617649
Lead Sponsor	Stanford University Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions	Hyperthermia
Enrollment	30 participants
Start Date	2026-06
Primary Completion	2028-06 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2026-06-01