Clinical Trial

The Efficacy and Safety of Female PRP Co-incubation With Sperm During (IUI) Cycles

Not Yet Recruiting
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Summary
The investigators hypothesize that infertility patients undergoing IUI who receive female autologous platelet-rich plasma (PRP) co-incubation with husband's sperm would have higher clinical pregnancy rate. Primary outcome: To compare the incidence of clinical pregnancy outcome in those infertility patients undergoing IUI with female PRP co-incubation with husband's sperm group and non-PRP group. Secondary outcomes: * To evaluate the post-culture sperm parameters between the intervention group and control group * To evaluate the IUI parameter between the intervention group and control group * To evaluate the safeness between the female PRP co-incubation with husband's sperm in the IUI group and non-PRP group, including potential infection rate or other pregnancy outcomes such as miscarriage, multiple pregnancy, ectopic pregnancy and molar pregnancy
Trial Details
NCT Number NCT07615634
Lead Sponsor Chinese University of Hong Kong
Conditions Reproductive Issues
Enrollment 288 participants
Start Date 2026-05-21
Primary Completion 2027-11-20 (estimated)
Study Completion 2028-05-20 (estimated)
Updated on ClinicalTrials.gov 2026-05-29