Uppsala Self-Screening of Cardiovascular Health

U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can identify clinically actionable cardiovascular risk factors more effectively than usual care. Participants randomized to the screening arm receive a home blood pressure measurement device, a dried blood spot sampling kit (for ApoB, HbA1c and creatinine), and a digital questionnaire. The control arm receives usual care. Recruitment runs 2024-2027 with a target identification of 10,000 cardiovascular risk conditions.

NCT Number	NCT07614659
Lead Sponsor	Johan Sundström Collaborators: Region Uppsala
Conditions	Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus, Atrial Fibrillation, Chronic Kidney Disease
Enrollment	45,000 participants
Start Date	2025-02-01
Primary Completion	2027-12 (estimated)
Study Completion	2037-12 (estimated)
Updated on ClinicalTrials.gov	2026-06-30