Clinical Trial

Imaging CRF X NOP Interactions in Alcohol Use Disorder

Recruiting Early Phase 1
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Summary
This positron emission tomography imaging study uses \[C-11\]NOP-1A and hydrocortisone to image stress-modulating proteins in heavy drinking alcohol use disorder (AUD) subjects and healthy controls (HC). It will also characterize the role of these stress-regulating proteins in a relapse to alcohol.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-05-22.
Trial Details
NCT Number NCT07612631
Lead Sponsor Rajesh Narendran
Collaborators: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions Alcohol Use Disorder
Enrollment 90 participants
Start Date 2026-06-01
Primary Completion 2031-06-30 (estimated)
Study Completion 2032-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-03