Clinical Trial

Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration

Recruiting
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Summary
This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar region. Sixteen patients requiring extraction and immediate implant placement will be randomly allocated into two groups. Clinical and radiographic outcomes including implant stability, peri-implant probing depth, modified bleeding index, marginal bone loss, buccal bone thickness, and bone density will be evaluated over a 9-month follow-up period.
Trial Details
NCT Number NCT07610876
Lead Sponsor Suez Canal University
Conditions Dental Implants, Immediate Implant Placement, Osseointegration
Enrollment 16 participants
Start Date 2025-08-11
Primary Completion 2026-10-10 (estimated)
Study Completion 2026-11-10 (estimated)
Updated on ClinicalTrials.gov 2026-05-28