Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation

The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical stimulation (EES) of the spinal cord to restore voluntary motor functions of upper and lower limbs in participants with chronic stroke suffering from mobility impairment. The goal is to establish a direct bridge between the motor intention of the participant and the spinal cord, which should not only improve or restore voluntary control of arm and leg movement and support immediate mobility, but also promote neurological recovery when combined with neurorehabilitation.

NCT Number	NCT07610850
Lead Sponsor	Ecole Polytechnique Fédérale de Lausanne
Conditions	Stroke, Hemiplegia
Enrollment	3 participants
Start Date	2026-09-01
Primary Completion	2028-10 (estimated)
Study Completion	2032-10 (estimated)
Updated on ClinicalTrials.gov	2026-06-08