Clinical Trial

Pneumoperitoneum Pressure and Lung Ultrasound Atelectasis

Recruiting
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Summary
Elective laparoscopic cholecystectomy may lead to perioperative atelectasis due to pneumoperitoneum-related diaphragmatic elevation and impaired respiratory mechanics. Lung ultrasound (LUS) provides a noninvasive bedside method for evaluating perioperative aeration loss. This prospective randomized controlled study aims to compare the effects of low-pressure (10 mmHg) and standard-pressure (14 mmHg) pneumoperitoneum on perioperative atelectasis assessed by LUS in patients undergoing laparoscopic cholecystectomy under general anesthesia. Changes in LUS scores, respiratory mechanics, oxygenation, and postoperative clinical outcomes will also be evaluated.
Protocol Amendment History 2 changes
critical Recruitment opened 2026-06-24
notable Enrollment increased: 76 -> 112 participants 2026-05-29
Trial Details
NCT Number NCT07609615
Lead Sponsor Engin Çetin
Conditions Atelectasis, Perioperative Complication, Pneumoperitoneum
Enrollment 112 participants
Start Date 2026-06-01
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-23