FLASH Pilot Phase 1 Safety Study

The primary purpose of this research trial is to study the safety of electron FLASH treatment for cutaneous lymphoma lesions. In addition, investigators will confirm the accuracy of dose and dose rate delivery of electron FLASH therapy using on-patient dosimetry measurements in combination with FAST camera imaging. Researchers will also determine the response rates of cutaneous lymphomas treated with a low radiation dose in a single fraction using electron UHDR treatments, followed by an assessment of radiation related skin toxicity.

NCT Number	NCT07608549
Lead Sponsor	Lesley A. Jarvis Collaborators: Dartmouth College
Conditions	Cutaneous Lymphoma
Enrollment	10 participants
Start Date	2029-10-31
Primary Completion	2030-12-31 (estimated)
Study Completion	2031-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-27