Impact of NOL - Nociception Level Index Intraoperative Monitoring on Perioperative Outcomes in Spine Surgery - a Quality Improvement Pilot

The objective of this study is to evaluate the clinical impact of the NOL nociception level index monitoring on intraoperative and post operative patient outcomes and institutional metrics when used to guide intraoperative analgesia dosing in patients undergoing spine surgery under general anesthesia when compared to a case controlled retrospective cohort.

NCT Number	NCT07608276
Lead Sponsor	Medasense Biometrics Ltd Collaborators: Thomas Jefferson Health
Conditions	Spine Surgery, Pain After Surgery, Anesthesia , Analgesia
Enrollment	100 participants
Start Date	2026-05
Primary Completion	2026-12 (estimated)
Study Completion	2027-03 (estimated)
Updated on ClinicalTrials.gov	2026-05-27