Clinical Trial

Rotary Versus Manual Degranulation in Alveolar Ridge Preservation

Active, Not Recruiting
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Summary
After a tooth is taken out, the empty socket needs to heal. Sometimes unhealthy soft tissue (called granulation tissue) is left behind and can slow down healing. This study compares two ways to clean the socket: 1. Manual method: a hand instrument (curette) 2. Rotary method: a small rotating dental bur Both methods are standard in dental practice. The study will see which method is faster, causes less pain, and leads to better bone healing. After cleaning, all patients will receive a routine bone graft to protect the jawbone for a possible future dental implant. The study will measure: * How long (in seconds) it takes to clean the socket * A harmless blue stain (Toluidine Blue) was used during cleaning to show any unhealthy tissue left behind, and cleaning continued until no stain remained; the stain showed when to stop rather than being measured on its own * Changes in the bone at 3 and 6 months, measured by a special three-dimensional X-ray (cone-beam computed tomography, CBCT) * Pain and swelling reported by patients in the first week after the procedure * Any side effects or healing problems Each extraction site is randomly assigned to one of the two cleaning methods (like flipping a coin), so a patient having two teeth treated may receive a different method at each. The surgeon knows which method is used, but the person analyzing the X-rays does not, to keep the results fair. The study included 50 adult patients and 60 extraction sites. Some patients had two teeth treated, at separate appointments. It is being conducted at the College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Protocol Amendment History 7 changes
notable Enrollment reduced: 60 -> 50 participants 2026-08-05
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-07-14
notable Primary completion moved earlier: 2026-08-31 -> 2026-07-09 2026-07-14
minor Completion moved earlier: 2027-03-01 -> 2027-01-09 2026-07-14
critical Recruitment opened 2026-06-04
notable Primary completion moved earlier: 2026-10-10 -> 2026-08-31 2026-05-28
minor Completion moved earlier: 2027-04-10 -> 2027-03-01 2026-05-28
Trial Details
NCT Number NCT07607314
Lead Sponsor Imam Abdulrahman Bin Faisal University
Conditions Chronic Periapical Periodontitis, Alveolar Ridge Preservation
Enrollment 50 participants
Start Date 2026-06-01
Primary Completion 2026-07-09 (estimated)
Study Completion 2027-01-09 (estimated)
Updated on ClinicalTrials.gov 2026-08-04