Influence of the Gut Microbiome on Blueberry Polyphenol Metabolites

The objective of this study is to determine whether inter-individual differences in the gut microbiome influence exposure to blueberry polyphenol metabolites. We will use pharmacokinetics of blueberry polyphenols after an acute blueberry exposure to group individuals into "metabotypes", groups of individuals based on similarity in their metabolite profiles. We will then use multi-omic approaches to determine whether the gut microbiome predicts an individual's metabotype.

NCT Number	NCT07607158
Lead Sponsor	Colorado State University Collaborators: Florida State University, National Center for Complementary and Integrative Health (NCCIH), University of Utah, King's College London
Conditions	Microbiome Analysis, Metabolomics
Enrollment	125 participants
Start Date	2026-01-27
Primary Completion	2027-03-01 (estimated)
Study Completion	2028-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-26