Clinical Trial

A Study to Assess the Safety, Tolerability and Efficacy of ION775

Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The main objective of this study is to evaluate the effect of ION775 on fasting triglyceride (TG) levels in participants with hypertriglyceridemia (HTG) and severe hypertriglyceridemia (sHTG).
Protocol Amendment History 2 changes
notable Trial sites expanded: 8 -> 16 locations 2026-06-19
notable Trial sites expanded: 3 -> 8 locations 2026-06-02
Trial Details
NCT Number NCT07604974
Lead Sponsor Ionis Pharmaceuticals, Inc.
Conditions Hypertriglyceridemia, Severe Hypertriglyceridemia
Enrollment 72 participants
Start Date 2026-05-12
Primary Completion 2027-09 (estimated)
Study Completion 2028-03 (estimated)
Updated on ClinicalTrials.gov 2026-06-18