Remimazolam-Propofol Combination Sedation for Gastrointestinal Endoscopy: A Prospective Observational Study

This prospective observational study evaluated the safety and efficacy of a remimazolam-propofol combination sedation protocol in adult patients undergoing elective gastrointestinal endoscopy at a tertiary care centre in Romania. The primary outcome was procedural completion. Secondary outcomes included time to sedation onset, recovery time, discharge readiness, total sedative doses administered, and incidence of adverse events including cardiovascular and respiratory complications.

NCT Number	NCT07604480
Lead Sponsor	University of Medicine and Pharmacy "Victor Babes" Timisoara
Conditions	Procedural Sedation, Gastrointestinal Endoscopy
Enrollment	29 participants
Start Date	2024-11-01
Primary Completion	2025-03-15 (estimated)
Study Completion	2025-03-15 (estimated)
Updated on ClinicalTrials.gov	2026-05-22