Trends in Transfusion Strategies and Outcomes in Trauma

This retrospective cohort study evaluated transfusion practices and outcomes in 137 severely injured trauma patients requiring massive transfusion at a Level I trauma center (2020-2025). This study analyzed balanced transfusion ratios, whole blood (WB) use, thromboelastography (TEG), and adjunctive hemostatic therapies to determine their impact on 30-day mortality and other clinical outcomes.

NCT Number	NCT07603999
Lead Sponsor	Mariah Arif
Conditions	Transfusion, Trauma Coagulopathy, Mortality, Blood Transfusion
Enrollment	137 participants
Start Date	2020-01-01
Primary Completion	2025-12-31 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-22