Efficacy and Safety of LP-005 Injection in Patients With Moderate-to-Severe Periodontitis

This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study designed to evaluate the clinical efficacy, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of multiple local injections of different doses of LP-005 injection in patients with moderate-to-severe periodontitis, and to investigate changes in biomarker levels.

NCT Number	NCT07603713
Lead Sponsor	Longbio Pharma (Suzhou) Co., Ltd.
Conditions	Periodontitis
Enrollment	100 participants
Start Date	2026-05-01
Primary Completion	2026-11-12 (estimated)
Study Completion	2027-03-23 (estimated)
Updated on ClinicalTrials.gov	2026-05-22