This study aims to evaluate dental anxiety and stress levels in children receiving regular piano training compared with children without piano training during preventive dental treatment. A total of 80 children aged 7-11 years, including 40 children receiving piano education and 40 controls, were included in the study. All participants underwent fissure sealant application using the Tell-Show-Do behavioral guidance technique. Dental anxiety was assessed before and after treatment using the Modified Child Dental Anxiety Scale-Faces Version (MCDASf), Facial Image Scale (FIS), and physiological parameters including pulse rate, blood pressure, oxygen saturation, and body temperature. Stress levels were evaluated using the PeSSKi scale. The study investigates whether regular piano education contributes to reduced dental anxiety and stress responses in pediatric dental patients.