The study hypothesis was that introducing the World Café teaching method into pharmacology education would significantly improve students' final examination scores, which included performance in accurate knowledge identification and discrimination, and in knowledge integration, reasoning and clinical decision-making, as well as students' subjective ratings of their pharmacology learning ability. This study evaluated the World Café method, a structured participatory teaching approach, in pharmacology education for nursing students, focusing on its impact on academic achievement and self-regulated learning.