Polarized Light Therapy for Radiation Dermatitis in Breast Cancer

This assessor-blinded randomized controlled trial aims to evaluate the efficacy of polarized polychromatic non-coherent light therapy as an adjunct to standard skin care in reducing acute radiation dermatitis in women with breast cancer undergoing hypofractionated whole-breast radiotherapy. Participants will be randomly allocated to receive either standard skin care alone or standard care combined with polarized light therapy initiated from the first radiotherapy session. Outcomes will include objective ultrasound-based dermal thickness measurements, clinical severity of radiation dermatitis using Radiation Therapy Oncology Group (RTOG) criteria.

NCT Number	NCT07600957
Lead Sponsor	Beni-Suef University
Conditions	Radio Dermatitis, Polarized Light, Breast Cancer Survivors
Enrollment	60 participants
Start Date	2026-05-21
Primary Completion	2027-01-15 (estimated)
Study Completion	2027-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-26