Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being

This is a clinical trial aimed to investigate if a novel phytochemical and fibre-rich snack can improve perimenopausal symptoms and well-being in perimenopausal women aged 40-55 and not on hormone replacement therapy. Hypothesis: The investigators hypothesise that the phytochemical and fibre-rich snack will improve perimenopausal symptoms via a gut microbiota mediated mechanism. Main research questions: Does eating the snack every day lower menopause symptoms such as hot flushes, night sweats, mood changes, and sleep problems? Does the snack improve mood, stress, anxiety, sleep, and overall quality of life? Does the snack improve the balance of bacteria in the gut, and could this be part of how it helps symptoms?

NCT Number	NCT07599930
Lead Sponsor	King's College London Collaborators: Tulā Code Ltd
Conditions	Perimenopause, Perimenopause-Related Depression, Mood, Sleep, Quality of Life, Gut -Microbiota
Enrollment	20 participants
Start Date	2026-04-24
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-05-20