Speech Amplification Devices for Parkinson Disease: Talker- and Technology-Driven Enhancements

The proposed research aims to investigate the use of speech amplification devices as a potential treatment option for people with Parkinson's disease and related disorders who exhibit hypophonia, a voice disorder that affects over half of those with Parkinson's disease. By characterizing the acoustic and perceptual effects of speech amplification and identifying ways to optimize outcomes through talker- and device-specific enhancements, this project seeks to develop personalized, evidence-based treatment options for hypophonia. The current proposal will move this effort forward by systematically eliciting and modifying speech amplification device output that leverage both behavioral and technological approaches.

NCT Number	NCT07599696
Lead Sponsor	Michigan State University Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions	Parkinson Disease, Atypical Parkinsonism
Enrollment	100 participants
Start Date	2024-03-01
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-20