Austrian PBC Registry

The goal of this registry is to better understand how primary biliary cholangitis develops over time, including the role of disease-related biomarkers, complications of the disease, and symptom burden. Patients with primary biliary cholangitis treated at participating centres in Austria will be invited to take part in this prospective registry. Participation in an associated biobank is optional. Clinical and laboratory data will be collected, and patients will be followed regularly through scheduled clinic visits. In addition, biological samples (serum, plasma, and, if available, liver tissue) may be collected and stored in the biobank for future research.

NCT Number	NCT07598669
Lead Sponsor	Medical University of Vienna Collaborators: WiGeV Klinik Ottakring, Medical University of Graz, Salzburger Universitätsklinkum, Universitätsklinikum St. Pölten, Kepler University Hospital, Klinikum Klagenfurt am Wörthersee, Klinikum Wels-Grieskirchen, Medical University Innsbruck, Ordensklinikum Linz GmbH Krankenhaus Barmherzige Schwestern, Krankenanstalt Rudolfstiftung
Conditions	Primary Biliary Cholangitis, Liver Cirrhosis, Portal Hypertension
Enrollment	500 participants
Start Date	2026-03-18
Primary Completion	2040-12 (estimated)
Study Completion	2040-12 (estimated)
Updated on ClinicalTrials.gov	2026-05-20