Clinical Trial

Evaluation of Post Operative Pain After Using Intracranial Cryotherapy During Single Visit RCT

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Summary
A total of 60 patients presenting with single-rooted teeth exhibiting symptomatic apical periodontitis were subjected to a randomized allocation into two groups of 30 each. Irrigation was done using 3% sodium hypochlorite for 5 seconds in all 60 teeth. Group 1 underwent final irrigation utilizing normal saline at room temperature. Group 2 received final irrigation using normal saline refrigerated between 2-5°C. Pain levels were assessed and recorded before the procedure and at 24 and 48-hour time intervals.
Trial Details
NCT Number NCT07598188
Lead Sponsor Islamabad Medical and Dental College
Conditions Periapical Diseases
Enrollment 60 participants
Start Date 2026-07-10
Primary Completion 2027-01-31 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-20