Fecal Microbiota Transplantation in Parkinson's Disease.

Fecal microbiota transplantation (FMT) is an effective and safe treatment for Clostridioides difficile infection (CDI). Though CDI is the only indication for FMT, more and more preliminary data on FMT in neurological disorders are reported due to gut-brain axis. This study is a pilot study to apply FMT on patients with Parkinson's disease (PD). The effect of FMT on motor and non-motor symptoms in PD will be also evaluated.

NCT Number	NCT07597421
Lead Sponsor	Chang Gung Memorial Hospital
Conditions	Parkinson's Disease
Enrollment	58 participants
Start Date	2026-09-01
Primary Completion	2029-04-07 (estimated)
Study Completion	2029-04-07 (estimated)
Updated on ClinicalTrials.gov	2026-05-19