Hematological Indices and Sympathetic Block Response in Neuropathic Pain

This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as part of routine clinical care. Hematological parameters including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), aggregate index of systemic inflammation (AISI), and red cell distribution width (RDW) will be evaluated before and after treatment. The association between changes in these indices and pain outcomes will be analyzed.

NCT Number	NCT07596823
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Enrollment	120 participants
Start Date	2026-06-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-29