Clinical Trial

Teprotumumab N01 Versus Methylprednisolone After Urgent Orbital Decompression for Dysthyroid Optic Neuropathy

Name: Teprotumumab N01 Versus Methylprednisolone After Urgent Orbital Decompression for Dysthyroid Optic Neuropathy — clinical trial record (NCT07594912)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Not Yet Recruiting Phase 2

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Summary

This study aims to evaluate the efficacy and safety of sequential Teprotumumab N01 compared with intravenous methylprednisolone (IVMP) after urgent orbital decompression in patients with dysthyroid optic neuropathy (DON).

Trial Details

NCT Number	NCT07594912
Lead Sponsor	Sun Yat-sen University
Conditions	Thyroid Eye Disease, TED, Graves Ophthalmopathy, Optic Neuropathy
Enrollment	60 participants
Start Date	2026-08
Primary Completion	2027-12 (estimated)
Study Completion	2028-04 (estimated)
Updated on ClinicalTrials.gov	2026-05-19