Clinical Trial

Normative Swallowing Physiological Metrics of Pharyngeal High-Resolution Impedance Manometry in Chinese Adults

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Summary
As Taiwan enters a super-aged society in 2025, the number of elderly patients and patients with multiple comorbidities continues to increase, and the risk of dysphagia rises with advancing age. Due to neuronal degeneration and muscle atrophy, older adults often experience delayed recovery of swallowing function after general anesthesia, and it may take up to seven days to regain their baseline swallowing ability. Therefore, postoperative monitoring of swallowing function and early rehabilitative intervention are crucial for reducing complication risks and facilitating early discharge. Currently, there is limited literature regarding normative data for pharyngeal swallowing assessment using high-resolution pharyngeal manometry with impedance as well as videofluoroscopic swallowing studies in the Chinese population. This project aims to recruit 80 healthy adults to establish normative reference values.
Trial Details
NCT Number NCT07594561
Lead Sponsor National Taiwan University Hospital
Conditions Hypopharyngeal Peak Pressure
Enrollment 80 participants
Start Date 2026-05-20
Primary Completion 2031-12-31 (estimated)
Study Completion 2032-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-19