Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic Cancer

Pelvic exenteration is an exceptionally extensive and very rare surgical procedure, most commonly used in the treatment of locally recurrent cervical cancer among gynecological malignancies. It is typically performed with curative intent when no other treatment options remain feasible. The aim of this study is to examine the quality of life and sexuality of patients who have undergone pelvic exenteration. This observational cross-sectional study utilizes internationally validated questionnaires assessing quality of life and sexual function: EORTC QLQ-C30, EORTC QLQ-CX24, and PISQ-12. The findings of this study will provide important guidance for the selection and planning of pelvic exenteration. Improved understanding of postoperative quality of life will support patient selection and enable more comprehensive and individualized patient counseling.

NCT Number	NCT07594327
Lead Sponsor	Tampere University Hospital
Conditions	Cervical Cancers, Vaginal Cancers, Vulvar Cancers, Endometrial Cancer, Gynecologic Cancers
Enrollment	21 participants
Start Date	2026-05
Primary Completion	2026-10 (estimated)
Study Completion	2026-10 (estimated)
Updated on ClinicalTrials.gov	2026-05-22