Combination vs. Monotherapy for Stenotrophomonas Maltophilia Infections

The goal of this multicentre observational study is to analyse the treatment strategies and the outcomes for patients with S. maltophilia infections using target trial emulation methodology. The main question it aims to answer is: • Does combined therapy achieve better results than monotherapy in treating S. maltophilia infections? Researchers will compare groups receiving monotherapy and combined therapy to see if there are differences in all-cause 30-day mortality.

NCT Number	NCT07593547
Lead Sponsor	Instituto de Investigación Sanitaria Gregorio Marañón
Conditions	Bloodstream Infection, Pneumonia - Bacterial, S Maltophilia Infections
Enrollment	790 participants
Start Date	2026-03-06
Primary Completion	2026-09-01 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-16